| Title |
Pregnancy increases the growth rates of world health organization grade II gliomas
|
|---|---|
| Published in |
Annals of Neurology, March 2010
|
| DOI | 10.1002/ana.21888 |
| Pubmed ID | |
| Authors |
Johan Pallud, Emmanuel Mandonnet, Christophe Deroulers, Denys Fontaine, Mathilde Badoual, Laurent Capelle, Frédérique Guillet‐May, Philippe Page, Philippe Peruzzi, Emmanuel Jouanneau, Marc Frenay, Stéphanie Cartalat‐Carel, Hugues Duffau, Luc Taillandier, Club de Neuro‐Oncologie de la Société Française de Neurochirurgie and the Association des Neuro‐Oncologues d'Expression Française |
| Abstract |
Twelve pregnancies in 11 adult women harboring World Health Organization (WHO) grade II gliomas (GIIGs) prior to pregnancy were reviewed to address whether pregnancy affects tumor growth using a quantitative approach of the radiological velocity of diametric expansion (VDE) on successive magnetic resonance images. VDE was significantly increased during pregnancy as compared to prepregnancy (p < 0.001) and to postdelivery (p = 0.012) periods. Pregnancy increases the radiological growth rates of GIIGs. An increase in seizure frequency was observed concomitantly in 40% of cases and further oncological treatment was started after delivery in 25% of cases. |
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Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 76 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 16% |
| Student > Postgraduate | 10 | 13% |
| Other | 9 | 12% |
| Researcher | 8 | 11% |
| Student > Master | 7 | 9% |
| Other | 18 | 24% |
| Unknown | 12 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 38% |
| Neuroscience | 9 | 12% |
| Agricultural and Biological Sciences | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Business, Management and Accounting | 2 | 3% |
| Other | 8 | 11% |
| Unknown | 20 | 26% |