Here's why I'm skeptical. In a GWAS we test a million variants for 1 trait so we set our significance cutoff at 0.05/1e6 = 5e-8 Here we're testing 1 SNP for 45 traits so a cutoff of 0.001 could be appropriate But smallest observed p is 0.03 @jlane_bos…
A quick literature search found many claims that the MTNR1B diabetes SNP (rs10830963) impacts sleep behaviors, referencing this paper by @jlane_boston and colleagues, but I'm skeptical https://t.co/d1l60qVN1H
@FructoseNo @BelindaFettke @Diabetescouk @drjasonfung @AnnChildersMD @MarikaSboros @drjoesDIYhealth @dr_kevinlee @DrAseemMalhotra @SugarByHalf Adding to your list of junk food, refined, and processed food: blue light in the evenings and/or eating at ni…
RT @SleepResearch_: Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology. https://t.co/lBEbbtIlxz