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Intrinsic versus Extrinsic Cancer Risks: The Debate Continues

Overview of attention for article published in Trends in Cancer, February 2016
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46 Mendeley
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Article details
Title
Intrinsic versus Extrinsic Cancer Risks: The Debate Continues
Published in
Trends in Cancer, February 2016
DOI 10.1016/j.trecan.2016.01.004
Pubmed ID
Authors
Abstract

Deciphering the relative contribution of intrinsic (e.g., genetic) and extrinsic (e.g., life style, environmental) risk factors in cancer development is crucial for strategizing cancer prevention. The recent publication by Wu and colleagues in Nature appears as an important contribution to the debate previously initiated by Tomasetti and Vogelstein in Science, who proposed that two-thirds of cancers can be attributed to random mutations and hence 'bad luck'. By contrast, Wu and colleagues, using four lines of evidence, suggest that cancer risk is dominated by extrinsic factors, and intrinsic risk factors only contribute marginally. The debate remains open, and an approach focusing on the evolutionary ecology of organs could provide crucial insights.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
France 2 4%
Unknown 44 96%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Researcher 9 20%
Student > Master 8 17%
Student > Ph. D. Student 7 15%
Other 3 7%
Student > Bachelor 2 4%
Other 4 9%
Unknown 13 28%
Readers by discipline
Readers by discipline Count As %
Agricultural and Biological Sciences 9 20%
Medicine and Dentistry 7 15%
Biochemistry, Genetics and Molecular Biology 6 13%
Environmental Science 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 3 7%
Unknown 15 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2016.
All research outputs
#14,771,207
of 25,371,288 outputs
Outputs from Trends in Cancer
#693
of 840 outputs
Outputs of similar age
#201,116
of 409,911 outputs
Outputs of similar age from Trends in Cancer
#18
of 19 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 840 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 409,911 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.