Heparin and Suramin Alter Plitidepsin Uptake Via Inhibition of GPCR Coupled Signaling

So why did Bayer not supply Suramin? #LongCovid

@Komplexmedizin @cstroeckw Remember suramin? Bayer owns it and would not supply the product for the trial. I believe it's a heparin mimetic. Coagulation is now the hot topic in Long Covid and also covid infection, as is JAK. (https://t.co/zjCDp23qPt

RT @MarkQuarter: Heparin and suramin alter plitidepsin uptake via inhibition of GPCR coupled signaling [2009. Robert Wood Johnson Medical…

Heparin and suramin alter plitidepsin uptake via inhibition of GPCR coupled signaling [2009. Robert Wood Johnson Medical School] plitidepsin binds to G-Protein Coupled Receptors (GPCRs), since GPCR & GRK inhibitors.. markedly reduce the drug uptak…