Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core

Overview of attention for article published in Bioorganic & Medicinal Chemistry Letters, August 2017

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New CNS penetrant M4 allosteric modulator from @tweetbasicsci investigators CW Lindsley & @jeffconn2 https://t.co/s4ySrjBppp

New CNS penetrant M4 allosteric modulator from @VICB_Vanderbilt members CW Lindsley & @jeffconn2 https://t.co/c956tQ7C86

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