To evaluate the effect of breathing 50 ppm carbon monoxide (CO) on exercise capacity in persons with anemia, 10 nonsmoking subjects with chronic anemia (mean hemoglobin 8.9 g%) were studied. No subject had heart or lung disease. By double-blind, randomized, crossover design, duration of fatigue-limited exercise after breathing CO and purified air for 1 hr was compared. Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing purified air, P less than 0.004. Mean exercise duration decreased from 270.8 to 221.0 sec after breathing CO in contrast to an increase from 267.9 to 271.6 sec after breathing purified air, P less than 0.0001. Hence, in the absence of clinical heart or lung disease, increasing carboxyhemoglobin concentrations aggravate exercise performance in nonsmokers with chronic anemia.
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2025.
All research outputs
#6,087,087
of 27,778,980 outputs
Outputs from Environmental Research
#2,715
of 8,717 outputs
Outputs of similar age
#3,042
of 41,486 outputs
Outputs of similar age from Environmental Research
#2
of 4 outputs
Altmetric has tracked 27,778,980 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 8,717 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.2. This one has gotten more attention than average, scoring higher than 63% of its peers.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.
