Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity

Overview of attention for article published in JCI Insight, July 2019

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Delighted to share our recent publication from the Gao Lab on how to reduce immune responses against AAVs, one of the most popular tools for delivering therapeutic genes #genetherapy #AAV #immuneresponse #Immunology https://t.co/KkxkRaGxsO

An AAV vector targeting antigen-presenting cell-specific miRNA binding reduces cellular immunity without activating humoral immunity https://t.co/XEdjXKbyB2 @UMMSGeneTherapy @UMassMedical #immunology #allergy #therapeutics

Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity. https://t.co/anvQZKzh9r

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