| Title |
Isolation of a new foamy retrovirus from orangutans
|
|---|---|
| Published in |
Journal of Virology, November 1994
|
| DOI | 10.1128/jvi.68.11.7124-7130.1994 |
| Pubmed ID | |
| Authors |
M O McClure, P D Bieniasz, T F Schulz, I L Chrystie, G Simpson, A Aguzzi, J G Hoad, A Cunningham, J Kirkwood, R A Weiss |
| Abstract |
We have isolated a new foamy virus from blood samples taken from two apparently healthy orangutans (Pongo pygmaeus). The older orangutan has since died with encephalopathy after a brief acute illness, while the younger one, his grandson, remains well. These animals and 12 other orangutans had specific antibodies to foamy virus as measured by immunofluorescence. The new foamy virus and the antisera showed strong and specific neutralization, with only weak cross-reaction with other simian foamy virus strains. Southern blotting with gag and env probes of human foamy virus and PCR amplification showed that the new foamy virus, designated SFV-11, is related to, yet distinct from, previously characterized strains from humans, chimpanzees, and monkeys. |
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Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 35 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 20% |
| Researcher | 7 | 20% |
| Professor | 5 | 14% |
| Student > Master | 3 | 9% |
| Student > Doctoral Student | 2 | 6% |
| Other | 5 | 14% |
| Unknown | 6 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 29% |
| Agricultural and Biological Sciences | 8 | 23% |
| Immunology and Microbiology | 3 | 9% |
| Veterinary Science and Veterinary Medicine | 2 | 6% |
| Medicine and Dentistry | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 8 | 23% |