Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates

Overview of attention for article published in Molecular Therapy, May 2019

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twitter: 3 X users

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@NaturePortfolio @Nature Wondering if someone would mind explaining how this work differs significantly from what others have done using zinc fingers and crispr-cas9 already in HSCs for sickle cell? https://t.co/qaOvsHIzhe https://t.co/33FGUPMnCw htt…

Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. https://t.co/9fSvppUNCd

Gene correction in engrafting #hematopoietic stem cells may be limited by the capacity of the cells to mediate homology-directed repair. https://t.co/MRwhSnFSfa @UCLA @MolTherapy https://t.co/H4Bz81nooc

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