A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions

Overview of attention for article published in Human Molecular Genetics, August 2012

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This paper has 4 comments on PubPeer, an open scientific commentary website.

Peer 3

14 May 2016

Yes they are. Francisca Diaz and Carlos T. Moraes

Unregistered Submission

10 May 2016

How does this explain the duplication? If simply the actin blot form the previous unsplit figure was used, wouldn't then be the actin blots for the RISPKO be equally similar? Yet they aren't...

Peer 3

29 Mar 2016

These series of blots were originally constructed as one figure, as the samples are the same (piriform cortex homogenates of mice at different ages)...

Peer 2

24 Mar 2016

yes this is a duplication; however, actin represents loading of the same biological samples, so it could be a valid control provided that all samples were probed on the same membrane

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