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Article details
Title
Augmenting Surgery via Multi-scale Modeling and Translational Systems Biology in the Era of Precision Medicine: A Multidisciplinary Perspective
Published in
Annals of Biomedical Engineering, March 2016
DOI 10.1007/s10439-016-1596-4
Pubmed ID
Authors
Abstract

In this era of tremendous technological capabilities and increased focus on improving clinical outcomes, decreasing costs, and increasing precision, there is a need for a more quantitative approach to the field of surgery. Multiscale computational modeling has the potential to bridge the gap to the emerging paradigms of Precision Medicine and Translational Systems Biology, in which quantitative metrics and data guide patient care through improved stratification, diagnosis, and therapy. Achievements by multiple groups have demonstrated the potential for (1) multiscale computational modeling, at a biological level, of diseases treated with surgery and the surgical procedure process at the level of the individual and the population; along with (2) patient-specific, computationally-enabled surgical planning, delivery, and guidance and robotically-augmented manipulation. In this perspective article, we discuss these concepts, and cite emerging examples from the fields of trauma, wound healing, and cardiac surgery.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
United States 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Researcher 11 17%
Student > Bachelor 9 14%
Student > Master 7 11%
Professor > Associate Professor 7 11%
Student > Doctoral Student 5 8%
Other 12 19%
Unknown 12 19%
Readers by discipline
Readers by discipline Count As %
Engineering 18 29%
Medicine and Dentistry 8 13%
Computer Science 4 6%
Biochemistry, Genetics and Molecular Biology 2 3%
Business, Management and Accounting 2 3%
Other 12 19%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2016.
All research outputs
#21,157,205
of 25,986,827 outputs
Outputs from Annals of Biomedical Engineering
#2
of 2 outputs
Outputs of similar age
#236,130
of 316,103 outputs
Outputs of similar age from Annals of Biomedical Engineering
#12
of 14 outputs
Altmetric has tracked 25,986,827 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2 research outputs from this source. They receive a mean Attention Score of 3.8. This one scored the same or higher as 0 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,103 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.