ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes

Overview of attention for article published in Journal of Clinical Investigation, July 2019

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In summary, we identified a novel mechanism by which ABCA1 deficiency contributes to cardiolipin accumulation and mitochondrial dysfunction, leading to podocyte injury and to the progression of DKD. https://t.co/mDEwJbHqoA

From Alessia Fornoni's group @umiamimedicine: Linking ATP-binding cassette A1 (ABCA1) deficiency to cardiolipin-driven mitochondrial dysfunction in diabetic kidney disease: https://t.co/D8KKDTusU3 https://t.co/5IhbVMN71B

RT @NatRevNeph: New #ResearchHighlight on lipids and podocyte damage in #DKD. https://t.co/DJ0Ci5Ajvy (original @jclinicalinvest article: h…

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