The amoeboflagellate Naegleria was one of the first organisms in which de novo basal body/centriole assembly was documented. When in its flagellate form, this single-celled protist has two flagella that are templated by two basal bodies. Each of these basal bodies is structurally well conserved, with triplet microtubules and well-defined proximal cartwheel structures, similar to most other eukaryotic centrioles. The basal bodies are anchored to the nucleus by a single, long striated rootlet. The Naegleria genome encodes many conserved basal body genes whose expression is induced prior to basal body assembly. Because of the rapid and synchronous differentiation from centriole-less amoebae to temporary flagellates with basal bodies, Naegleria offers one of the most promising systems to study de novo basal body assembly, as well as the mechanisms regulating the number of centrioles assembled per cell.
Pharmacology, Toxicology and Pharmaceutical Science
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2%
Other
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Unknown
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Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2016.
All research outputs
#17,796,099
of 22,860,626 outputs
Outputs from Cilia
#67
of 91 outputs
Outputs of similar age
#206,071
of 300,360 outputs
Outputs of similar age from Cilia
#8
of 9 outputs
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So far Altmetric has tracked 91 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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