Computational analysis and interactive visualization of biological networks and protein structures are common tasks for gaining insight into biological processes. This protocol describes three workflows based on the NetworkAnalyzer and RINalyzer plug-ins for Cytoscape, a popular software platform for networks. NetworkAnalyzer has become a standard Cytoscape tool for comprehensive network topology analysis. In addition, RINalyzer provides methods for exploring residue interaction networks derived from protein structures. The first workflow uses NetworkAnalyzer to perform a topological analysis of biological networks. The second workflow applies RINalyzer to study protein structure and function and to compute network centrality measures. The third workflow combines NetworkAnalyzer and RINalyzer to compare residue networks. The full protocol can be completed in ∼2 h.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2012.
All research outputs
#15,242,707
of 22,663,969 outputs
Outputs from Nature Protocols
#2,478
of 2,726 outputs
Outputs of similar age
#100,187
of 156,786 outputs
Outputs of similar age from Nature Protocols
#36
of 41 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,726 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
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