Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial

Yet another example of why we need RCTs and not just observational studies to inform clinical practice. Reminiscent of the lack of efficacy of immune plasma for influenza: https://t.co/8QpW0Bekwk

@GermHunterMD Key theme - desperation to find plausible therapy and not recognizing the existing data. While observational studies in pandemics suggested benefit, prospective studies didn’t find benefit (https://t.co/r2BTz2541h).

RT @AaronRichterman: Serious q - I hear a lot of people saying convalescent plasma probably works for cov2, but is there any high quality c…

There’s actually a VERY limited number of illnesses where we proven it works... we shouldn’t float our boat too much - plenty where we give plasma, it’s std of care because there is nothing else, not because it’s proven efficacious