LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells

Overview of attention for article published in Science Advances, October 2019

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LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription published as: https://t.co/4liTjvsZB5 @ScienceAdvances #biorxiv

@bmart87 @dkjhaunc I would say LEDGF, as it behaves as FACT when cells are FACT free 😂 https://t.co/PRiQ80FWEo

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. Both contain a Kme mark reading PWWP motif, an Integrase Binding Domain, and two AT-hooks reminiscent of a highly conserved KR-rich C-terminal CTCF AT-hook …

RT @rs_meyer: New FACT-like factors identified at @ReinbergDanny lab, bringing together old school biochemistry and genomics to further our…

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