降尿酸首选别嘌醇？如何避免超敏反应?
Sohu News,
在 2020 年 ACR 的痛风治疗指南中，别嘌醇被作为一线降尿酸药物推荐 [1] ，但由于在黄种人中，别嘌醇因可引发致死性超敏反应，令不少医生对这一药物望而却步，甚至有医生表示：「不作第一个处方别嘌醇的医生」。 但是，包括今年新发布的《痛风基层合理用药指南…
Hypersensitivity Reactions and Gout Tx: Watch the Dose
MedPage Today,
Both allopurinol and febuxostat (Uloric) were associated with an increased risk of hypersensitivity reactions among new users…
Adding Allopurinol Safe, Effective in IBD
MedPage Today,
Action Points Adjunctive allopurinol is safe, effective, and well tolerated in inflammatory bowel disease patients who do not…
To Treat or Not to Treat (to Target) in Gout
Annals of Internal Medicine,
Gout, the most common form of inflammatory arthritis, has well-understood pathophysiology and effective treatments available.