I read an interesting article in the British Neuroscience Association magazine about Angry Fish. Research is being carried out on Zebrafish to identify a new drug treatment for aggression. You can also read an article in Science Direct - https://t.co/…
"In summary, we have demonstrated that juvenile zebrafish are a suitable model to screen for novel drugs to reduce aggression, with the potential to uncover the neural circuits and signalling pathways that mediate such behavioural effects." https://t.…
In a study using a behavioural platform in a phenotypic screen to identify drugs that can reduce zebrafish aggression without affecting locomotion, it was discovered that caffeine and sildenafil can selectively reduce aggression https://t.co/MvcE0sCG8D
"Imaging studies revealed that both caffeine and sildenafil are active in the zebrafish brain, with prominent activation of the thalamus and cerebellum evident." https://t.co/pDnRZbky2C