A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model

Overview of attention for article published in The Journal of Pharmacology and Experimental Therapeutics, August 2019

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Patients w/nonalcoholic steatohepatitis exhibit altered hepatic protein expression of metabolizing enzymes & transporter & altered xenobiotic PKs. This study assesses effects of NASH & silymarin on the disposition of the model OATP substrate…

RT @NaPDICenter: Patients w/nonalcoholic steatohepatitis exhibit altered hepatic protein expression of metabolizing enzymes & transporter &…

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