Phase I Trial of a Modified Vaccinia Ankara Priming Vaccine Followed by a Fowlpox Virus Boosting Vaccine Modified to Express Brachyury and Costimulatory Molecules in Advanced Solid Tumors https://t.co/Pzb9EC1xnI https://t.co/R2XPXfHaH3
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Congrats to Chris and all who are involved in making these trials happen. Great to see further successes with the brachyury vaccine strategies!
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Brachyury is a protein that, in humans, is encoded by the TBXT gene. In prostate cancer brachyury expression is associated with Gleason score, perineural, invasion and capsular invasion. It is also associated with resistance to cytotoxic chemotherapy.
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