New article: Neuron-autonomous susceptibility to induced synuclein aggregation is exacerbated by endogenous Lrrk2 mutations and ameliorated by Lrrk2 genetic knock-out. https://t.co/CNtvZP7Bm0 #parkinsons #neurology https://t.co/V2HOHVCUxb
@austenmilnerwoo & collaborators report mouse LRRK2 knockout neurons are more resistant to #Parkinsons-associated α-synuclein aggregation, while G2019S-LRRK2 knockin neurons are more vulnerable to fibril-induced α-synuclein accumulation https://t.co/O…
MacIsaac et al. just published in @braincomm their work done at @TheNeuro_MNI about "Neuron-autonomous susceptibility to induced synuclein aggregation is exacerbated by endogenous Lrrk2 mutations and ameliorated by Lrrk2 genetic knock-out" . Find it 😃at …