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We had previously shown that TGFb-driven myofibroblasts increase their uptake and utilization of glutamine for TCA cycle anaplerosis and proline biosynthesis to promote collagen translation (2/X). https://t.co/4tLDe68WDS
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RT @embojournal: #TGF beta signaling stimulates #glutamine #metabolism for proline biosynthesis, a process that buffers excessive #mitochon…
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Proline biosynthesis is a vent for TGFβ‐induced mitochondrial redox stress | The EMBO Journal https://t.co/bR4Jt8tD4Z