| Title |
Fluid overload and changes in serum creatinine after cardiac surgery: predictors of mortality and longer intensive care stay. A prospective cohort study
|
|---|---|
| Published in |
Critical Care, May 2012
|
| DOI | 10.1186/cc11368 |
| Pubmed ID | |
| Authors |
Anna Stein, Lucas Vieira de Souza, Cassian Rodrigues Belettini, Willian Roberto Menegazzo, Júlio Rosales Viégas, Edemar Manuel Costa Pereira, Renato Eick, Lilian Araújo, Fernanda Consolim-Colombo, Maria Cláudia Irigoyen |
| Abstract |
ABSTRACT: INTRODUCTION: Fluid overload is a clinical problem frequently related to cardiac and renal dysfunction. The aim of this study was to evaluate fluid overload and changes in serum creatinine as predictors of cardiovascular mortality and morbidity after cardiac surgery. METHODS: Patients submitted to heart surgery were prospectively enrolled in this study from September 2010 through August 2011. Clinical and laboratory data were collected from each patient at preoperative and trans-operative moments and fluid overload and creatinine levels were recorded daily after cardiac surgery during their ICU stay. Fluid overload was calculated according to the following formula: (Sum of daily fluid received (L) - total amount of fluid eliminated (L)/preoperative weight (kg) × 100). Preoperative demographic and risk indicators, intra-operative parameters and postoperative information were obtained from medical records. Patients were monitored from surgery until death or discharge from the ICU. We also evaluated the survival status at discharge from the ICU and the length of ICU stay (days) of each patient. RESULTS: A total of 502 patients were enrolled in this study. Both fluid overload and changes in serum creatinine correlated with mortality (odds ratio (OR) 1.59; confidence interval (CI): 95% 1.18 to 2.14, P = 0.002 and OR 2.91; CI: 95% 1.92 to 4.40, P <0.001, respectively). Fluid overload played a more important role in the length of intensive care stay than changes in serum creatinine. Fluid overload (%): b coefficient = 0.17; beta coefficient = 0.55, P <0.001); change in creatinine (mg/dL): b coefficient = 0.01; beta coefficient = 0.11, P = 0.003). CONCLUSIONS: Although both fluid overload and changes in serum creatinine are prognostic markers after cardiac surgery, it seems that progressive fluid overload may be an earlier and more sensitive marker of renal dysfunction affecting heart function and, as such, it would allow earlier intervention and more effective control in post cardiac surgery patients. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 20% |
| Japan | 1 | 20% |
| Spain | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 2% |
| France | 1 | <1% |
| Switzerland | 1 | <1% |
| Italy | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 108 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 15% |
| Other | 16 | 14% |
| Researcher | 13 | 11% |
| Student > Postgraduate | 13 | 11% |
| Student > Ph. D. Student | 11 | 10% |
| Other | 29 | 25% |
| Unknown | 15 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 76 | 67% |
| Nursing and Health Professions | 6 | 5% |
| Engineering | 5 | 4% |
| Agricultural and Biological Sciences | 2 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | <1% |
| Other | 5 | 4% |
| Unknown | 19 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2021.
All research outputs
#7,778,510
of 25,374,647 outputs
Outputs from Critical Care
#4,173
of 6,554 outputs
Outputs of similar age
#53,332
of 179,088 outputs
Outputs of similar age from Critical Care
#35
of 113 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
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We're also able to compare this research output to 113 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.