DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo

Overview of attention for article published in Human Molecular Genetics, March 2020

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📢Check out the last publication from @SanderHouten lab with my lab mate Joao Leandro as 1st author. A biochemical study aimed to inhibit DHTKD1 for Glutaric Aciduria type 1 therapy. + description of a new ketoacid dehydrogenase complex https://t.co/vOQL6…

RT @JIMD_Editors: Our “borrowed” paper: DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogen…

Our “borrowed” paper: DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo João Leandro, @SanderHouten report on substrate reduction therapy in #glutaricaciduria type 1 https://t.co/PMcHS6j…

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