herbal medicines have being used for different illnesses. However, standardization of these medicaments should be overcome before introducing for treatment purposes. Ajwain essential oil is traditionally used for neuropathic pain.
To develop and assess a gas chromatographic-based method for the quantification of thymol in Ajwain essential oil, current work was performed.
Both pure thymol and Ajwain creams were prepared and again undergone hydrodistillation method under temperature-controlled procedure to re-extract the applied essential oil and pure thymol. Previously, Ajwain seeds essential oil composition were analyzed and identified using GC/MS. After re-extraction, GC/FID was applied to quantitatively determine the thymol content in the Ajwain and thymol creams. Parameters represented by International Conference on Harmonization (ICH) guidelines were considered for the determination.
Thymol content in a 50 g laminated tube of Ajwain cream was calculated as 2.34 g ± 0.02. Regarding to total thymol content of a 50 g laminated tube of Thymol cream (2.43 g), recovery percent for Ajwain cream was calculated as 96.29 %.
using hydrodistillation of an essential oil containing cream sample via Clevenger was found a simple and convenient method to work up and extract active volatile components of such semisolid formulation. However, the extraction yield is profoundly related to the condenser temperature. The current employed determination method is introduced as a rapid and reliable method and thus, can be suggested for the quality control assessment of phytopharmaceutical semisolid preparations containing thymol and similar volatile constituents.
Pharmacology, Toxicology and Pharmaceutical Science
1
17%
Nursing and Health Professions
1
17%
Agricultural and Biological Sciences
1
17%
Neuroscience
1
17%
Unknown
2
33%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2016.
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#28,227,862
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#203
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#348,630
of 446,610 outputs
Outputs of similar age from Current Drug Discovery Technologies
#9
of 14 outputs
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So far Altmetric has tracked 292 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
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