We've been using them as a tool to understand how evolution can switch the catalytic metal-preference. It does so by changing residues in the secondary coordination sphere (close, but not touching the metal)... : https://t.co/5ETMO6WG4v https://t.co/Asj…
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Then we studied that pair in biochemical detail to identify residues in the metal’s secondary coordination sphere that had changed during neofunctionalisation to change its metal-preference: https://t.co/5ETMO6WG4v https://t.co/YTa2wDwLpl
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Recent publications: 2017: https://t.co/9HCOAhtfWQ 2020: https://t.co/XrlhSmD4oR 2023: https://t.co/OmwJQMFrXk
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New paper by Barwinska-Sendra et al. says "S. aureus NCTC8325 virulence factors (PATRIC, and VFDB databases), and essential genes (PATRIC and AureoWiki databases) annotations were downloaded from the respective databases on 29th March, 2019." https://t.…