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Reduction of anxiety-like and depression-like behaviors in rats after one month of drinking Aronia melanocarpa berry juice

Overview of attention for article published in Food & Function, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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Title
Reduction of anxiety-like and depression-like behaviors in rats after one month of drinking Aronia melanocarpa berry juice
Published in
Food & Function, January 2016
DOI 10.1039/c6fo00321d
Pubmed ID
Authors

Mirko Tomić, Đurđica Ignjatović, Gordana Tovilović-Kovačević, Dijana Krstić-Milošević, Slavica Ranković, Tamara Popović, Marija Glibetić

Abstract

The treatment of mood and anxiety disorders by nutraceuticals is gaining growing awareness. Berries of Aronia melanocarpa (Black chokeberry) and their extracts, exceptionally abundant in diverse phenolic compounds, have become famous for the highest in vitro antioxidant activity among fruits and notable health benefits (e.g. anti-diabetic, anti-inflammatory, cardioprotective). This study was designed to investigate the behavioral effects of month-long unlimited consumption of Aronia master juice (AJ) and/or juice reconstruct without polyphenols (RJ), in young male rats. AJ was initially evaluated for its content of phenolic compounds by spectrophotometric assays and HPLC-DAD. Rats that were supplied with three various water concentrations of AJ and RJ, respectively: 20% + 0% (ARO group), 5% + 15% (RAJ) and 0 + 20% (PLC), were compared with those which consumed only water (CTL). Daily drinking of AJ solution was significantly elevated from the second or third week onward, which was most expressed in the ARO group. Only this group displayed behavioral variations, manifested by certain hyperactivity in open field tests and prominent reductions of anxiety-like behaviors in the elevated plus maze. The ARO rats also expressed an alleviation of depression-like behavior in forced swimming tests. These findings demonstrate the beneficial behavioral effects of the one-month-long free drinking of phenolic-rich AJ in rats (>20 ml per kg b. mass daily) that may be recognized as stimulating, anxiolytic-like and antidepressant-like. The in vitro assays suggested that MAO-A/MAO-B inhibitions by the phenolic compounds of AJ might be the possible in vivo mechanisms for such behavioral actions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Serbia 1 2%
Unknown 61 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 19%
Student > Bachelor 11 18%
Student > Ph. D. Student 9 15%
Student > Master 6 10%
Other 5 8%
Other 4 6%
Unknown 15 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 23%
Medicine and Dentistry 7 11%
Nursing and Health Professions 6 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Veterinary Science and Veterinary Medicine 1 2%
Other 6 10%
Unknown 24 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2023.
All research outputs
#3,029,689
of 24,257,963 outputs
Outputs from Food & Function
#449
of 4,660 outputs
Outputs of similar age
#51,249
of 402,351 outputs
Outputs of similar age from Food & Function
#45
of 372 outputs
Altmetric has tracked 24,257,963 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,660 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 402,351 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 372 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.