| Title |
Complement Inhibitors from Scabies Mites Promote Streptococcal Growth – A Novel Mechanism in Infected Epidermis?
|
|---|---|
| Published in |
PLoS Neglected Tropical Diseases, July 2012
|
| DOI | 10.1371/journal.pntd.0001563 |
| Pubmed ID | |
| Authors | |
| Abstract |
Scabies is highly prevalent in socially disadvantaged communities such as indigenous populations and in developing countries. Generalized itching causes discomfort to the patient; however, serious complications can occur as a result of secondary bacterial pyoderma, commonly caused by Streptococcus pyogenes (GAS) or Staphylococcus aureus. In the tropics, skin damage due to scabies mite infestations has been postulated to be an important link in the pathogenesis of disease associated with acute rheumatic fever and heart disease, poststreptococcal glomerulonephritis and systemic sepsis. Treatment of scabies decreases the prevalence of infections by bacteria. This study aims to identify the molecular mechanisms underlying the link between scabies and GAS infections. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 1% |
| Unknown | 76 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 14% |
| Student > Master | 9 | 12% |
| Researcher | 7 | 9% |
| Student > Bachelor | 6 | 8% |
| Lecturer | 4 | 5% |
| Other | 15 | 19% |
| Unknown | 25 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 27% |
| Agricultural and Biological Sciences | 12 | 16% |
| Immunology and Microbiology | 7 | 9% |
| Veterinary Science and Veterinary Medicine | 2 | 3% |
| Environmental Science | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 27 | 35% |