To determine the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and the likelihood of postoperative complications and fracture re-operation rate in orthopaedic trauma patients receiving vitamin D and calcium supplementation.
retrospective case series SETTING:: Level I trauma center, Midwestern United States PATIENTS:: All orthopaedic trauma patients - 18 years or older - over a 20-month period were included with available initial and repeat 25(OH)D serum levels. In total, 201 patients met inclusion criteria.
All patients received 1000 IU of vitamin D3 and 1500 mg of calcium daily. Vitamin D deficient and insufficient patients also received 50,000 IU of ergocalciferol (vitamin D2) weekly until 25(OH)D levels normalized or fractures healed.
fracture complications and 25(OH)D levels.
Fifteen patients experienced post-operative healing complications. There was no significant difference between initial (p=0.92) or repeat (p=0.91) 25(OH)D levels between patients with and without fracture healing complications. Twenty eight patients required repeat orthopaedic surgery. There was no significant difference between initial (p=0.62) or repeat (p=0.18) 25(OH)D levels between patients who did or did not require repeat orthopaedic surgery. There was no significant difference between initial (p=0.66) or repeat (p=0.89) 25(OH)D levels between patients who did or did not require non-orthopaedic surgery.
Serum 25(OH)D levels did not significantly affect the likelihood of fracture healing complications requiring surgery or any non-orthopaedic injury-related surgery.
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2016.
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