| Title |
Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models
|
|---|---|
| Published in |
BMC Medicine, July 2012
|
| DOI | 10.1186/1741-7015-10-80 |
| Pubmed ID | |
| Authors |
Parul Gupta, Sanjay K Srivastava |
| Abstract |
HER2 is an oncogene, expression of which leads to poor prognosis in 30% of breast cancer patients. Although trastuzumab is apparently an effective therapy against HER2-positive tumors, its systemic toxicity and resistance in the majority of patients restricts its applicability. In this study we evaluated the effects of phenethyl isothiocyanate (PEITC) in HER2-positive breast cancer cells. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 29% |
| United Kingdom | 2 | 29% |
| United States | 1 | 14% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Practitioners (doctors, other healthcare professionals) | 2 | 29% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 63 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 20% |
| Student > Ph. D. Student | 11 | 17% |
| Student > Bachelor | 8 | 13% |
| Student > Postgraduate | 6 | 9% |
| Student > Master | 6 | 9% |
| Other | 5 | 8% |
| Unknown | 15 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 25% |
| Agricultural and Biological Sciences | 14 | 22% |
| Biochemistry, Genetics and Molecular Biology | 7 | 11% |
| Immunology and Microbiology | 3 | 5% |
| Chemistry | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 14 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2014.
All research outputs
#2,398,552
of 22,671,366 outputs
Outputs from BMC Medicine
#1,552
of 3,397 outputs
Outputs of similar age
#16,177
of 164,599 outputs
Outputs of similar age from BMC Medicine
#27
of 44 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,397 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,599 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.