Abstract B168: The PARP inhibitor, niraparib, crosses the blood brain barrier in rodents and is efficacious in a BRCA2-mutant intracranial tumor model

Overview of attention for article published in Molecular Cancer Therapeutics, December 2015

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@kenyulin @IJGConline Thanks! Great question. I don't think we have clinical data in ovarian cancer yet. In a preclinical study in rodents seems like niraparib crossed the blood-brain barrier better. But difficult to tell it's clinical significance in H…

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