Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle

Overview of attention for article published in Biochemical Journal, June 2011

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RT @ChrisPerryMito: Classic estimates of mitochondrial ADP sensitivity (Km: <20uM) suggest we live at 50% of mitochondrial 'VO2max' when at…

Classic estimates of mitochondrial ADP sensitivity (Km: <20uM) suggest we live at 50% of mitochondrial 'VO2max' when at rest. Impossible. Controlling other cytoplasmic factors (cytoskeleton?), in vitro rigor issue and phosphate shuttling solves the r…

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