That may be because there are no reasonable pharmacokinetics for ivermectin treatment for COVID. [https://www.ncbi.nlm.nih.gov/p…
Pred rokom som sa dostal do debaty o ivermektine, az do bodu, ze som sa donutil najst si a nastudovat si relevantne studie a…
He more than likely won't. The fact of the matter is that even when he first had Pierre Kory on, there was already suspicion…
No, that's not what you said. You're implying that if we just tinker with the dosage we can get ivermectin to work just like…
Those same studies fail to point out[¹](https://sciencebasedmedicine.org/ivermectin-is-the-new-hydroxychloroquine/) that the…
This is a non-story: Non-clinical research; aka not patients in clinics. We've known from the get-go that there is a mechanism…
So this is a pretty long review, but it does a pretty good job of aggregating the material. The Cochrane review also reviewed…
I can't find the study about the fatal dose anymore, but…
https://pubmed.ncbi.nlm.nih.gov/31960060/ And here is a study that shows ocular effects (albeit mild) at just 2x the maximum…
Problem is that Ivermectin only works against COVID at doses high enough to cause blindness and intestinal sloughing. Sure, no…
https://pubmed.ncbi.nlm.nih.gov/32378737/ Here is one of many; abstract only. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404…
The mechanism is irrelevant if the pharmacokinetics and pharmacodynamics are unsuited. If the concentration of ivermectin…
You've got to take in silico and in vitro studies with a grain of salt. Just because an agent has a potential antiviral effect…
There you go https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14476 https://pubmed.ncbi.nlm.nih.gov/12362927/
The untitled "quote" doesn't say the opposite. It says that there are some indications that there may be therapeutic benefits…
So you provide no sources but complain I am not providing sources? We are talking in the context of covid, if you did not…
And by ground-breaking study, you mean a meta-analysis of mostly small, poorly conducted studies in 3rd world nations. There…
> Can someone ELI5? These fruitcakes don't trust the vaccine so they're planning to catch covid and take an anti worm horse…
[This image says it all.](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/7404744/bin/BCP-9999-na-g001.jpg) As the dosage…
Whoa, a comp chem paper? A topic I can actually address given my education?! Don't mind if I take a stab at it! So what this…
It wouldn't be compassionate use, because it's available. There isn't one drug company that you need to get permission from to…
Here ya go! https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14476 > Although high doses of ivermectin in adults or…
> And if it turns out it does help, even a little bit, then think of how horrible it will be that people died while a cheap…
Your first link is not a study itself, but merely a single page paper citing other studies that seem to show Ivermectin acting…
[Link](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404744/pdf/BCP-9999-na.pdf) “the free plasma concentration of ivermectin…
I think I finally [found it.](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404744/pdf/BCP-9999-na.pdf) I think this might be…
Just wanted to point this out. The studies relating to ivermectin having antiviral properties are entirely in vitro. The way it…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404744/pdf/BCP-9999-na.pdf Pretty difficult to reach those concentration in vivo.
>Ivermectin is a broad-spectrum antiparasitic agent approved by the Food and Drug Administration (FDA) of the USA proved to be…
**Similarly with this article - which provides some nuance, which has earlier been lacking in mainstream articles.** …
In vitro activity is irrelevant if you cannot feasibly reach therapeutic concentration in vivo without causing toxicity: https:…
I extracted a couple of the links embedded in the article for further reading. https://academic.oup.com/cid/advance-article/doi…
Hi, not an expert in Bayesian analysis. I might however add my 2 cents. The first thing to note is that ivermectin is an (Stromec…
The antiviral effect seen in vitro is not feasible to reach at the "safe" doses it is usually administered as as an…
Video: https://www.youtube.com/watch?v=VS2-QxAM41Y Medical exemptions and…
Respondendo novamente agora que tive tempo de dar uma lida, [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404744/](https://www.n…