Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in Drosophila

Overview of attention for article published in eLife, June 2016

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[hal-01446113] Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in Drosophila by K Narbonne-Reveau et al. https://t.co/ogod7RWnJ2

We first found that NB tumors actually originate from a subset of intermediate progenitors that only exists during an early period of larval development. They are produced by neural stem cells during a period that is delineated by an intrinsic clock htt…

Together with our previous publication https://t.co/kMDkAkvR3R, we tried to answer 2 important questions in the field of pediatric CNS cancers: i.Why is the incidence of CNS cancers much higher in children than in adults (~25% vs 2% of all cancers)? /2

Breakthrough answers age old question how neural stem cells 'break bad' to become #cancer stem cells! #science https://t.co/uWgMOuEt10

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