| Title |
Probiotics in neonatology
|
|---|---|
| Published in |
Journal of Paediatrics & Child Health, August 2012
|
| DOI | 10.1111/j.1440-1754.2012.02508.x |
| Pubmed ID | |
| Authors |
Leah Hickey, Susan E Jacobs, Suzanne M Garland, on behalf of the ProPrems Study Group |
| Abstract |
Probiotics are micro-organisms that confer health benefits on the host. Postulated mechanisms include: increasing resistance of the mucosal barrier to migration of bacteria and their toxins by strengthening intestinal cell junctions, modification of host response to microbial products, augmentation of immunoglobulin A mucosal responses, enhancement of enteral nutrition to inhibit the growth of pathogens; production of antimicrobial proteins; and competitive exclusion of potential pathogens. Published meta-analyses and systematic reviews report the effects of probiotics on important clinical outcomes in neonates. This paper will review the evidence for probiotic supplementation in neonatology, with a focus on preterm infants. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Argentina | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| Brazil | 1 | 1% |
| Unknown | 77 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 16% |
| Student > Ph. D. Student | 9 | 11% |
| Other | 7 | 9% |
| Student > Doctoral Student | 6 | 8% |
| Researcher | 6 | 8% |
| Other | 14 | 18% |
| Unknown | 25 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 34% |
| Agricultural and Biological Sciences | 12 | 15% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Immunology and Microbiology | 3 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 8 | 10% |
| Unknown | 25 | 31% |