FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
Cell,
Adult humans with inherited, complete FLT3L deficiency enable valuable insights into the role of the hematopoietic growth…
A Human Protein Found in Non-Immune Cells Defends Against COVID-19
HHMI News,
Scientists have found that cells that line human lungs and other tissues express a protein that can halt SARS-CoV-2 replication…
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors
Cell,
Severe COVID-19 can reprogram hematopoiesis and establish epigenetic memory in hematopoietic stem and progenitor cells (HSPC…
Rare Primary Immunodeficiency Diseases and COVID-19: Evolving Insights and Implications for Clinical and Public Health Practice
Genomics and Health Impact Blog,
In this post, we explore how new research on rare genetic diseases is contributing to our understanding of COVID-19 occurrence…
Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
Cell,
Studies in humans with interferon regulatory factor 1 (IRF1) deficiency reveal differences in how type I and type II…
Todo lo que tienes que saber sobre la reinfección de COVID-19
Well - New York Times,
Tenemos las respuestas para tus preguntas más urgentes.
You Can Get Covid Again. Here’s What to Know About Reinfection.
Well - New York Times,
Some reinfection questions, answered.
Cross-Reactive and Mono-Reactive SARS-CoV-2 CD4+ T Cells in Prepandemic and COVID-19 Convalescent Individuals
Science in Seattle,
Class II tetramer reagents for eleven common DR alleles and a DP allele prevalent in the world population were used to identify…
Irish scientists among global group hunting for genetic explanation to COVID-19 resistance
Trinity News and Events,
Irish scientists are among a global group hunting for a genetic explanation as to why some people seem resistant to COVID-19…
Il 20% dei morti per Covid è dovuto ad anticorpi “impazziti” che ostacolano la risposta immunitaria
Scienze fanpage,
Lo dimostrano due studi pubblicati su Science Immunology dal Covid Human Genetic Effort, un consorzio internazionale coordinato…
It’s Not All about Microbes: Genetics and susceptibility to infections
Science in the News,
by Aleks Procherafigures by Shreya Mantri The past year and a half have been a time of profound uncertainty. We all wish we…
Host Genomics and COVID-19: One Year Later
Genomics and Health Impact Blog,
Unprecedented global research collaborations in human genomics provide a model for research in response to a pandemic. Early…
Monogenic immune defects in type I interferon pathways as a risk factor for severe COVID-19 pneumonia
BrainImmune: Trends in Neuroendocrine Immunology,
In the 23 October 2020 issue of Science, Zhang et al. report on early results of the COVID Human Genetic Effort (www.covidhge.com…
When it comes to COVID, nurture trumps nature – so far
Genetic Literacy Project,
‘Like a fire alarm and a sprinkler system all in one’: Immune proteins keep some COVID patients from getting seriously ill
Genetic Literacy Project,
‘Breakthrough Finding’ Reveals Why Certain COVID Patients Die
Physician's Weekly,
Dr. Megan Ranney has learned a lot about COVID-19 since she began treating patients with the disease in the emergency…
'Breakthrough finding' offers clues about why certain COVID-19 patients die
Booster Shots - latimes.com,
What makes some COVID-19 patients so much sicker than others? In some cases, people are more vulnerable because their immune…
Why Does COVID-19 Kill Some People and Save Others?
Whats New,
Researchers think they have come a step closer to understanding why the new coronavirus kills some people and saves others. In…
Coronastream: long COVID, waves around the world and genetic predisposition to pneumonia
Microbe Post,
In this special blog series, medical microbiologists led by Dr Tim Inglis summarise some of the research that will be essential…
Predicting the Outcome of COVID-19: GigaScience at the Human Cell Atlas COVID-19 Virtual Symposium
Giga Science Journal,
The Human Cell Atlas is a consortium that aims to “create comprehensive reference maps of all human cells—the fundamental units…
1 in 7 COVID patients have genetic flaws that dramatically increase their vulnerability
Genetic Literacy Project,
TWiV 671: Prizes, polio, and a pandemic puzzle
This Week in Virology with Vincent Racaniello,
Daniel Griffin provides a clinical report on COVID-19, then Amy joins us to discuss the 2020 Chemistry Nobel Prize for gene…
Round-up: COVID-19 October 2020 (Part One)
Front Line Genomics,
President Donald Trump caught “a blessing from God” (COVID-19) and the UK is on the verge of another national lockdown – a lot…
September Update for Inborn Errors of Immunity
Immunoglitch,
38 PUBMED indexed articles were published in the month of September 2020.COVID-19 and PIDZang et al report defects in TLR3- and…
Rogue Antibodies and Gene Mutations Explain Some Cases of Severe COVID-19
NIH Director's Blog,
Caption: Colorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 virus particles (yellow)…
Bazı Ciddi COVID-19 Vakalarının, Genetik Mutasyonlar veya Vücuda Saldıran Antikorlarla Bağlantılı Olduğu Keşfedildi!
Evrim Ağacı,
COVID-19'a neden olan SARS-CoV-2 virüsü…
Why do some people suffer worse from COVID-19? New studies identify a genetic mutation
Age of Engagement | Big Think,
Since the pandemic began, we've wondered why some people suffer terribly while others show no symptoms. A team at the Howard…
Suomalaistutkimuksen häkellyttävä löytö: interferonivaste voi kertoa, miksi joku saa vakavan koronataudin – tätä se tarkoittaa
iltalehti.fi,
Tiede saattaa olla löytänyt yhden merkittävän syyn siihen, miksi korona voi olla erityisen vaarallinen miehille ja vanhoille.
Ťažký priebeh COVID-19 môžu spôsobiť nenápadné mutácie aj škodlivé protilátky. Ohrození sú najmä muži
Denník N,
Cukrovka, obezita či respiračné problémy sú časté priťažujúce okolnosti pri ochorení COVID-19. V nemocniciach sa však ocitajú…
Covid-19 : des anomalies génétiques et immunologiques responsables de 15% des formes graves
Daily Science,
Durée de lecture : 3 min Pourquoi la réponse à l’infection par le virus SARS-CoV2 varie-t-elle autant d’une personne à l’autre ?
Rejtett immungyengeséget fedeztek fel a súlyos COVID-betegek 14 százalékánál
Qubit,
A COVID-19-világjárvány kezdete óta foglalkoztatja a tudósokat, vajon mekkora szerepet játszik az emberi test egyik első védvonal…
Covid-19: scoperto perché alcuni pazienti sviluppano una forma particolarmente grave di malattia
Meteo Web,
Un consorzio internazionale di ricercatori, coordinati dal National Institute of Allergy and Infectious Diseases (NIAID) e…
25th September – the COVID-19 coronavirus compendium
Nature Microbiology Community,
Re-infection with common cold coronaviruses, inborn errors of the interferon response, and deaths due to pollution
Le forme gravi di COVID-19 sono in parte dovute alla genetica: speranza per nuove terapie
Scienze fanpage,
Un team di ricerca internazionale guidato da scienziati dell'Università Rockfeller di New York ha scoperto che dietro una parte…
#MSCOVID19: Interferon-beta and NABs
Multiple Sclerosis Research,
Barts-MS rose-tinted-odometer: ★ It is always nice to see evidence supporting a hypothesis you had more than a decade ago…
We May Finally Know a Molecular Reason Why COVID-19 Is So Deadly, But Only For Some
Science Alert,
This could make a huge difference.
Scientists Discover Genetic and Immunologic Underpinnings of Some Cases of Severe COVID-19
Bioengineer,
NIH Investigator Co-Led International Research…
Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body
Bioengineer,
Credit…
Scientists trace severe COVID-19 to faulty genes and an autoimmune condition
Bioengineer,
Credit: The Rockefeller…
Some Severe COVID-19 Cases Linked to Genetic Mutations or Antibodies that Attack the Body
HHMI News,
Two new studies offer an explanation for why COVID-19 cases can be so variable. A subset of patients has mutations in key…
Scientists discover genetic and immunologic underpinnings of some cases of severe COVID-19
NIH News Releases,
NIH investigator co-led international research effort.