Title |
Are statins anti-inflammatory?
|
---|---|
Published in |
Trials, November 2000
|
DOI | 10.1186/cvm-1-3-161 |
Pubmed ID | |
Authors |
Gavin J Blake, Paul M Ridker |
Abstract |
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone. Emerging evidence from both clinical trials and basic science studies suggest that statins have anti-inflammatory properties, which may additionally lead to clinical efficacy. Measurement of markers of inflammation such as high sensitivity C-reactive protein in addition to lipid parameters may help identify those patients who will benefit most from statin therapy. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 20% |
United Kingdom | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | 3% |
United States | 1 | 2% |
Unknown | 55 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 17% |
Student > Master | 9 | 16% |
Researcher | 8 | 14% |
Student > Bachelor | 8 | 14% |
Other | 4 | 7% |
Other | 12 | 21% |
Unknown | 7 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 38% |
Agricultural and Biological Sciences | 8 | 14% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Immunology and Microbiology | 3 | 5% |
Neuroscience | 3 | 5% |
Other | 9 | 16% |
Unknown | 9 | 16% |