Resequencing analysis of the candidate tyrosine kinase and RAS pathway gene families in multiple myeloma

This paper still haunts me. https://t.co/o0o5sE1viT We cloned a very active Ras mutation that was a tandem dup that would have been missed by clinical screening. So much genetic dark matter!!

Resequencing analysis of candidate tyrosine kinase & RAS pathway gene families in #Myeloma http://t.co/y7SFqKAY HT @Myeloma_Doc

Resequencing of #myeloma cells finds mutations in KRAS, PIK3CA, INSR, LTK, and MERTK, including 7 new KRAS mutations (http://t.co/Y6mUZtfk).