ARF4-mediated intracellular transport as a broad-spectrum antiviral target
Nature Behind the Paper,
Nature Microbiology, Published online: 19 February 2025; doi:10.1038/s41564-025-01940-wARF4 GTPase activity is needed for…
SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle
Ecology & Evolution Community - Springer Nature,
This article describes how ORF3a, an accessory protein of SARS-CoV-2, acts as a virulence factor and contributes to the…
Nutrient-regulated control of lysosome function by signaling lipid conversion
Cell,
A nutrient-regulated PI(3)P/PI(4)P lipid switch at lysosomes triggers the conversion between motile mTORC1 signaling-active…
SARS-CoV-2 İnsan Hücrelerine Nasıl Giriyor? Kendini Nasıl Kopyalıyor? Delta Varyantı Bağışıklık Sistemini Nasıl Atlatabiliyor?
Evrim Ağacı,
SARS-CoV-2.
How a Medication for OCD Ended Up in a Covid-19 Trial
Feed: All Latest,
In a small study, the drug kept patients with mild symptoms from worsening. If it holds up in a larger test, it could help keep…
Coronaviruses hijack lysosomes to exit cells
NIH Research Matters,
Researchers discovered that coronaviruses hijack lysosomes, the cell’s trash disposal system, to exit cells and spread through…
COVID SCIENCE-Common cold antibodies hold clues to COVID-19 behavior; lung scans speed COVID-19 diagnosis in stroke patients
Devdiscourse,
The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and…
NIH scientists discover key pathway in lysosomes that coronaviruses use to exit cells
NIH News Releases,
Targeting cells’ ‘trash compactor’ could lead to new antiviral strategy to fight COVID-19.