Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

RT @RobTownley6: @Biorealism @virologyanon @gadyepstein Holtz I guess he is having an impact. @gadyepstein as others have mentioned Dr. Pie…

@Biorealism @virologyanon @gadyepstein Holtz I guess he is having an impact. @gadyepstein as others have mentioned Dr. Pierce is not communicating science he is I believe the term is...bloviating. Look no further than the points he raises about early ad…

@ProtonicStorm @pathogenetics @0bj3ctivity @EduEngineer @WIRED @sergeilkp @kumar_lab @MichaelWorobey @ScienceMagazine @sciencecohen @mnt @WmHaseltine @quay_dr @edwardcholmes @MarionKoopmans @trvrb @EricTopol Facts are: “transition frequency of D614G occ…

@slav3331 @PiotrWitczak_ @AgnieszkaSzust3 To pan się douczy, bo braki ogromne :) https://t.co/jCaJJ0yRGo https://t.co/686YnTcd2M

@pafigo_ @PiotrWitczak_ @AgnieszkaSzust3 Skończmy ta nierówną dyskusję . Pan podstaw nie zna. "B.1 to wariant z mutacją D614G ". To bzdura. D614G jest mutacja wewnątrz linii B.1 sarscov2😂😂 https://t.co/X1eVqQh4Mk https://t.co/nVGswDqDSv

RT @VV_Radicalis: References: 1. https://t.co/pfq4EY1tCG 2. https://t.co/LI1xCytUS8 3. https://t.co/tOtNPEwiB0 4. https://t.co/XflTPptHSb…

References: 1. https://t.co/pfq4EY1tCG 2. https://t.co/LI1xCytUS8 3. https://t.co/tOtNPEwiB0 4. https://t.co/XflTPptHSb 5. https://t.co/D39xBaqzgA 6. https://t.co/DnT3fDeOQn 7. https://t.co/grPPfeF5sY 8. https://t.co/xIxxG9GqhK 9. https://t.co/8gP8WI4xl9

Recent publications: Transmissibility & pathogenicity of Dg14G Spike Mutation https://t.co/g6eRdyWPeT Introductions of #SARSCoV2 from Mainland Europe into Scotland https://t.co/Gg6CC9ATGU Zika causes Demyelination and axonal injury https://t.co/…

@fiona_chembot How about “phase 1” SARS-CoV-2, efficient spreaders due to the lack of previous host immunity [& enhanced early by S:D614G https://t.co/SG9JUwE4RU] vs "phase 2", VOCs et al better adapted for human transmission in the context of increas…

@MackayIM @UQ_News @RACGP Pardon me, D614G only increased viral load, not hospitalizations or deaths, statistically. The two often go hand in hand, though. I'm placing most of my hopes in an RdRp-based perfect vaccine and that the current ones hold out…

RT @MoritzGerstung: During the first wave in the spring ‘20 @erikmvolz observed that a lineage with a spike mutation D614G grew spread aro…

Effects of SARSCoV2 Spike Mutatn D614G on Transmissibility-Pathogenicity:⬆️freq of D614G consistent with selective advtg;Phylodynamic analyses don’t show diff growth D614G cluster;no asso of D614G replace with⬆️severity with⬆️viral load & young age ht…

During the first wave in the spring ‘20 @erikmvolz observed that a lineage with a spike mutation D614G grew spread around 15% faster than other lineages. This lineage was termed B. >> https://t.co/W1i6h3O8z8

@JT_Grindrod @LeezartTime @fallenigloos @amymaxmen @NateSilver538 I think you're reaching a bit relative to the actual data within human samples (as opposed to in vitro research). The precise impact of D614G remains a bit unclear. See these articles f…

Citations: D614G - https://t.co/yAgJryHmJz UK - https://t.co/90dzCZAb7p Indian - https://t.co/f5nytpX1pG https://t.co/xyT33D8AcZ

Amazing talk by @emcat1 at #Microbio21 on #SARSCoV2 epidemiology in the UK

Characterizing #SARSCoV2 mutants in the UK... D614G - https://t.co/WxTQKOwZZS N439K - https://t.co/l4AUiaZ0Rg (Emma Thomson) #Microbio21

@MartinaSisters @AlexandraJAlva4 @2dedostesta @soltysik_rob please join this party with nice and independent people 🙏

@AntibioticDoc Yeah I thought it was kind of an odd piece. Yeah, it's time for sleep because it's 1:57 am now...and I have https://t.co/2ECJTtQ32H to read for tomorrow. . . or a good novel. I have a lot of those too. :P https://t.co/sBvWTfppvW

RT @lalani_safina: @jameshamblin I said before. I'm afraid of this. https://t.co/2ECJTu7Erh

@jameshamblin I said before. I'm afraid of this. https://t.co/2ECJTu7Erh

RT @2dedostesta2: So, D614G was already circulating & being sampled when D614 popped up, although the dominant strain in China was D614, to…

So, D614G was already circulating & being sampled when D614 popped up, although the dominant strain in China was D614, to later be extinguished, since D614G was more transmissible than D614. Did I got this right ? Happy ☝️ year of investigating SARS-…

"The D614G mutation is associated with the B.1 lineage of SARS-CoV-2" https://t.co/diHQ5fiWqT "viruses from lineage B happen to have been sequenced and published first" https://t.co/7y4WqmLJpG https://t.co/3fNwfS0CUa

@misizuri @MarcBrup Wenn Ihnen Long Covid nicht reicht, dann bringen Sie sich mal auf Stand bezüglich der Mutanten und deren Zielgruppe. https://t.co/g8DiPHUOI9 "The D614G replacement is associated with higher viral loads and younger patient age".

@networkjungle @eorphelin Des travaux ont fait l'hypothèse que la mutation G614 rendait également le virus plus transmissible. https://t.co/22HPGYpkOa

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

@Stitchitvon_ @marcelbar8 Laten we het hopen, muterende varianten breken door bepaalde vaccins heen. Het is nog onduidelijk hoe en hoeveel, maar zomaar even naar het normale leven terug is een illusie, net als al die ongefundeerde beloftes van farmaceu…

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

Really thorough analysis of D614G - bottom line likely some increased transmissibility and higher viral load. Greater proportion of young pts - perhaps reflection of increased viral load - more testing (fewer asymptomatic)

#SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @CellCellPress https://t.co/t3woq2UIzl | #2021_ReCapJan https://t.co/XAVbdcDM55

https://t.co/U9GDrusICF

RT @profshanecrotty: 4. For comparison, the D614G mutant causes a 2 to 4 times increase in nasal viral load. https://t.co/4GBCSxQduH htt…

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

#SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @CellCellPress https://t.co/t3woq2UIzl https://t.co/h44e1D97DC

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

#SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @CellCellPress https://t.co/t3woq2UIzl https://t.co/Fe0u4QZ1co

@SinoInc has developed a comprehensive panel of #SARSCoV2 Spike Mutant Proteins, including D614G, Y453F, N501Y, and many others. More to come! Keep track of all mutant proteins here: https://t.co/XkZrqOQpXa #COVID19 #coronavirus #mutation #spike #D614G…

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

@lillithfairlive Here are some relevant (but hyperspecific) preprints: https://t.co/B2kI4Q2VVW https://t.co/bJvwTAUi9f https://t.co/daCl8hEJ2f https://t.co/jOUwf3yJGk

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

A recent paper published on @CellPressNews demonstrates that #SARSCoV2 D614G has no association with greater severity of infection, but with higher viral loads and younger patient age

RT @mmw_lmw: #SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @Cel…

#SARSCoV2 Transmissibility and Pathogenicity | Evaluating the Effects of #SpikeMutation D614G | Thomas Connor @cardiffuni @CellCellPress https://t.co/t3woq2UIzl https://t.co/ZYUOUFvmKv

RT @ykfrs1217: @minesoh （専門用語で失礼します。）「変異株の割合が増えた」だけだと創始者効果や遺伝的浮動の可能性が多分にありますが、「絶対数として感染者が増える」のは創始者効果では説明できません。D614Gでは、前者の可能性が高いまま残っています 1:h…

@minesoh （専門用語で失礼します。）「変異株の割合が増えた」だけだと創始者効果や遺伝的浮動の可能性が多分にありますが、「絶対数として感染者が増える」のは創始者効果では説明できません。D614Gでは、前者の可能性が高いまま残っています 1:https://t.co/HNs2TLHdIZ 2:…

A recent paper published on @CellPressNews demonstrates that #SARSCoV2 D614G has no association with greater severity of infection, but with higher viral loads and younger patient age #COVID19 #CoronavirusStrain #mutation https://t.co/zbOJOjgbyl

RT @CellCellPress: #Analysis of the spread and frequency of #SARSCoV2 D614G in the #UK. Out now! https://t.co/qY0vtRwRCa @erikmvolz @imperi…

#COVID19 ゲノム疫学の世界センターロンドンから、現行主流 #D614G の意義に結論。選択アドバンテージ仮説を支持、しかし重症化起因仮説は否定。ただし、若者へのウイルス高負荷の原因になっただろう、と。#E484K ・ #N501Y は同じ方向を加速している？：ICL。 https://t.co…

RT @keyaki1117: メモ「伝染性と病原性に対する新型コロナウイルスのスパイク変異D614Gの影響評価」 (Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility a…

RT @frank1522: @DrJulioSandoval @tvnnoticias https://t.co/RRJl3HAEch

@DrJulioSandoval @tvnnoticias https://t.co/RRJl3HAEch

Interesting... https://t.co/34Dmz54VDr

RT @fvguima: https://t.co/TyMnG7vilW https://t.co/2r4FhzD5aY

https://t.co/TyMnG7vilW https://t.co/2r4FhzD5aY

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity https://t.co/PsGotFxDxS

RT @keyaki1117: メモ「伝染性と病原性に対する新型コロナウイルスのスパイク変異D614Gの影響評価」 (Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility a…

メモ「伝染性と病原性に対する新型コロナウイルスのスパイク変異D614Gの影響評価」 (Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity) https://t.co/jt7qvZRIIl

RT @CellCellPress: #Analysis of the spread and frequency of #SARSCoV2 D614G in the #UK. Out now! https://t.co/qY0vtRwRCa @erikmvolz @imperi…

Sobre la mutación D614G: no parece afectar ni a la mortalidad inducida por el virus ni a la gravedad clínica de los enfermos, aunque sí aparece una mayor carga vírica si el paciente es joven https://t.co/sS6ajOw0sV

RT @CellCellPress: #Analysis of the spread and frequency of #SARSCoV2 D614G in the #UK. Out now! https://t.co/qY0vtRwRCa @erikmvolz @imperi…

#SARSCoV2 D614G in the #UK

RT @CellCellPress: #Analysis of the spread and frequency of #SARSCoV2 D614G in the #UK. Out now! https://t.co/qY0vtRwRCa @erikmvolz @imperi…

#Analysis of the spread and frequency of #SARSCoV2 D614G in the #UK. Out now! https://t.co/qY0vtRwRCa @erikmvolz @imperialcollege For all @CellPressNews #coronavirus research and commentary, visit https://t.co/BCdU2ltXnp #COVID19 https://t.co/nsYrWqcLYx

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity: Cell The D614 polymorphism in the SARS-CoV-2 Genome may increase transmissibility but not severity of the disease. https://t.co/TLAxFFMGK1

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmiss... https://t.co/5lmXrV9W19

@JosepBargallo https://t.co/M56PG4BA0r

論文も出てる。すぐ出てきたのはこの辺。 https://t.co/sBGwyfe3JF https://t.co/9fL6PNKUQo

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity https://t.co/ESucyIRZJT

@smitspatrick1 @laulam94 @vrtnws https://t.co/nRugtwBbod https://t.co/NG1dgGaxeI

The variant carrying D614G mutation became the predominant circulating variant. This mutation increases interaction of the receptor binding domain (RBD) of the viral spike protein with the human angiotension-converting enzyme 2 (hACE2) https://t.co/bw3d…

RT @profshanecrotty: 4. For comparison, the D614G mutant causes a 2 to 4 times increase in nasal viral load. https://t.co/4GBCSxQduH htt…

Now this is wild

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

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