Intranasal Treatment with Poly(I·C) Protects Aged Mice from Lethal Respiratory Virus Infections

Overview of attention for article published in Journal of Virology, August 2012

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https://t.co/OMx65iw5Jq

1/n Stimulation of innate and adaptive immune response during a viral infection. "Greater than 90% of all deaths from influenza A virus (IAV) occur in the elderly (>65 years of age)." https://t.co/aO8LESSu4g

RT @gerdosi: “mortality in 12- to 22-month-old mice infected with SARS-CoV or IAV was reduced from 80 to 100% to 0 to 10% by treatment with…

“mortality in 12- to 22-month-old mice infected with SARS-CoV or IAV was reduced from 80 to 100% to 0 to 10% by treatment with a TLR3 agonist, poly(I·C), with concomitant increased expression of interferon (IFN) and other proinflammatory molecules” https:…

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