Severe Acute Respiratory Syndrome Coronavirus 2–Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells

Overview of attention for article published in Journal of Infectious Diseases, December 2020

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@hjelle_brian @yeangtehcho This is about Mph & DC from peripheral blood. I get that alveolar might be of specific interest, but given vascular/endothelial tropism, my semi-educated guess is that this matters. 1/ https://t.co/Ck1AoY0SjE

@hjelle_brian @yeangtehcho I thought that SARS-CoV-2 doesn't frequently infect macrophages productively, but that unproductive infection kills them. I'd say that targets them, for destruction.... https://t.co/Ck1AoXIJ5w

@Hosenmaus1 @DerfelTheMighty Ja, das kann man so unterscheiden. Wird auch intensiv bei Macrophagen diskutiert, die viel Virus aufnehmen, aber kaum produktive Replikation zeigen. Siehe https://t.co/rXxDzAHTa8, wir haben das im Rahmen von https://t.co/hZL…