| Title |
Dynamic biomaterials: toward engineering autonomous feedback
|
|---|---|
| Published in |
Current Opinion in Biotechnology, March 2016
|
| DOI | 10.1016/j.copbio.2016.02.032 |
| Pubmed ID | |
| Authors | |
| Abstract |
Dynamic biomaterials are biocompatible engineered systems capable of sensing and actively responding to their surrounding environment. They are of growing interest, both as models in basic research to understand complex cellular systems and in medical applications. Here, we review recent advances in nano-scale and micro-scale biomaterials, specifically artificial cells consisting of compartmentalized biochemical reactions and biologically compatible hydrogels. These dynamic biomaterials respond to stimuli through triggered reactions, reaction cascades, logic gates, and autonomous feedback loops. We outline the advances and remaining challenges in implementing such 'smart' biomaterials capable of autonomously responding to environmental stimuli. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| United Kingdom | 1 | 1% |
| Spain | 1 | 1% |
| Unknown | 95 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 21 | 21% |
| Student > Ph. D. Student | 16 | 16% |
| Researcher | 11 | 11% |
| Student > Bachelor | 10 | 10% |
| Student > Doctoral Student | 6 | 6% |
| Other | 14 | 14% |
| Unknown | 20 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 17 | 17% |
| Biochemistry, Genetics and Molecular Biology | 13 | 13% |
| Chemistry | 10 | 10% |
| Agricultural and Biological Sciences | 9 | 9% |
| Materials Science | 7 | 7% |
| Other | 17 | 17% |
| Unknown | 25 | 26% |