The Rcs stress response inversely controls surface and CRISPR–Cas adaptive immunity to discriminate plasmids and phages

Overview of attention for article published in Nature Microbiology, January 2021

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2/ We previously identified regulators of type III-A (csm/cas) expression in Serratia using SorTn-seq 🧬(https://t.co/3ZRSOA6M8C). We discovered a host of regulators, including the Rcs pathway, which repressed all native CRISPR-Cas systems (III-A & I-…

RT @rafapinilla92: @vdlorenzo_CNB Bacteria can influence what type of MGE comes in (plasmid/phage) & when to be more promiscuous, ie permit…

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