| Title |
Pigmented Villonodular Synovitis
|
|---|---|
| Published in |
JBJS Reviews, July 2016
|
| DOI | 10.2106/jbjs.rvw.15.00086 |
| Pubmed ID | |
| Authors | |
| Abstract |
Evidence now exists suggesting a neoplastic origin for pigmented villonodular synovitis, including a thorough description of the translocations involved. Arthroscopic excision for localized pigmented villonodular synovitis allows for both minimal recurrence and morbidity when compared with open excision; however, open excision still plays an important role in treating posterior compartment nodules. The optimal surgical treatment for diffuse pigmented villonodular synovitis is still a matter for debate, with combined anterior arthroscopic and open posterior excision being considered the preferred method. Radiation therapy has re-emerged as an additional treatment method for pigmented villonodular synovitis; however, the potential for serious toxicity makes it a questionable option, especially for such a benign condition. Small molecule and monoclonal antibody targeted therapies are being investigated as novel treatment methods for pigmented villonodular synovitis, with promising results. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 40% |
| Rwanda | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 84 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 11 | 13% |
| Researcher | 9 | 11% |
| Student > Master | 7 | 8% |
| Other | 6 | 7% |
| Student > Ph. D. Student | 6 | 7% |
| Other | 17 | 20% |
| Unknown | 28 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 42 | 50% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Engineering | 2 | 2% |
| Business, Management and Accounting | 1 | 1% |
| Agricultural and Biological Sciences | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 34 | 40% |