MAIT cell activation augments adenovirus vector vaccine immunogenicity

Overview of attention for article published in Science, January 2021

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MAIT cell activation augments adenovirus vector vaccine (Oxford AZ) immunogenicity. This is why the success in curtailing mortality in uK 🇬🇧 https://t.co/KLrGu9W3W3

We found that ChAdOx1 (+ other serotypes) activate Vd2+ gdT cells in a process that depends on type I interferon, TNF, and IL-18. This continues work from last year (https://t.co/hX9WLoa2ur) where we report that Ad vectors activate MAIT cells by identic…

RT @emilyethornton: Lovely talk at @bsicongress #OIS, @nprovine! Acknowledging the people who helped with the work before the talk is super…

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