Title |
Fusarium spp infections in a pediatric burn unit: nine years of experience
|
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Published in |
Brazilian Journal of Infectious Diseases, May 2016
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DOI | 10.1016/j.bjid.2016.04.004 |
Pubmed ID | |
Authors |
María Teresa Rosanova, Martín Brizuela, Mabel Villasboas, Fabian Guarracino, Veronica Alvarez, Patricia Santos, Jorge Finquelievich |
Abstract |
Fusarium spp are ubiquitous fungi recognized as opportunistic agents of human infections, and can produce severe infections in burn patients. The literature on Fusarium spp infections in pediatric burn patients is scarce. To describe the clinical and epidemiological features as well as outcome of Fusarium spp infections in pediatric burn patients. Retrospective, descriptive study of Fusarium spp infections in a specialized intensive care burn unit. In 15 patients Fusarium spp infections were diagnosed. Median age was 48 months. Direct fire injury was observed in ten patients. The median affected burn surface area was 45%. Twelve patients had a full thickness burn. Fourteen patients had a Garces Index ≥3. Fungal infection developed at a median of 11 days after burn injury. Fungi were isolated from burn wound in 14 patients and from the bone in one patient. Amphotericin B was the drug of choice for treatment followed by voriconazole. Median time of treatment completion was 23 days. One patient (7%) died of fungal infection-related causes. In our series Fusarium spp was an uncommon pathogen in severely burnt patients. The burn wound was the most common site of infection and mortality was low. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 37 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 16% |
Researcher | 4 | 11% |
Other | 4 | 11% |
Student > Doctoral Student | 2 | 5% |
Student > Postgraduate | 2 | 5% |
Other | 5 | 14% |
Unknown | 14 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 32% |
Nursing and Health Professions | 4 | 11% |
Agricultural and Biological Sciences | 3 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Immunology and Microbiology | 1 | 3% |
Other | 1 | 3% |
Unknown | 14 | 38% |