Title |
Mobile genetic elements related to carbapenem resistance in Acinetobacter baumannii
|
---|---|
Published in |
Brazilian Journal of Microbiology, July 2016
|
DOI | 10.1016/j.bjm.2016.06.005 |
Pubmed ID | |
Authors |
Mariana Pagano, Andreza Francisco Martins, Afonso Luis Barth |
Abstract |
Acinetobacter baumannii is widely recognized as an important pathogen associated with nosocomial infections. The treatment of these infections is often difficult due to the acquisition of resistance genes. A. baumannii presents a high genetic plasticity which allows the accumulation of these resistance determinants leading to multidrug resistance. It is highlighted the importance of the horizontal transfer of resistance genes, through mobile genetic elements and its relationship with increased incidence of multidrug resistant A. baumannii in hospitals. Considering that resistance to carbapenems is very important from the clinical and epidemiological point of view, the aim of this article is to present an overview of the current knowledge about genetic elements related to carbapenem resistance in A. baumannii such as integrons, transposons, resistance islands and insertion sequences. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 195 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 33 | 17% |
Student > Ph. D. Student | 29 | 15% |
Student > Bachelor | 24 | 12% |
Researcher | 21 | 11% |
Student > Doctoral Student | 13 | 7% |
Other | 36 | 18% |
Unknown | 41 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 46 | 23% |
Immunology and Microbiology | 39 | 20% |
Agricultural and Biological Sciences | 22 | 11% |
Medicine and Dentistry | 22 | 11% |
Environmental Science | 4 | 2% |
Other | 18 | 9% |
Unknown | 46 | 23% |