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Atypical manifestations of Epstein–Barr virus in children: a diagnostic challenge

Overview of attention for article published in Jornal de Pediatria, January 2016
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Title
Atypical manifestations of Epstein–Barr virus in children: a diagnostic challenge
Published in
Jornal de Pediatria, January 2016
DOI 10.1016/j.jped.2015.06.007
Pubmed ID
Authors

Vasileios Bolis, Christos Karadedos, Ioannis Chiotis, Nikolaos Chaliasos, Sophia Tsabouri

Abstract

Clarify the frequency and the pathophysiological mechanisms of the rare manifestations of Epstein-Barr virus infection. Original research studies published in English between 1985 and 2015 were selected through a computer-assisted literature search (PubMed and Scopus). Computer searches used combinations of key words relating to "EBV infections" and "atypical manifestation." Epstein-Barr virus is a herpes virus responsible for a lifelong latent infection in almost every adult. The primary infection concerns mostly children and presents with the clinical syndrome of infectious mononucleosis. However, Epstein-Barr virus infection may exhibit numerous rare, atypical and threatening manifestations. It may cause secondary infections and various complications of the respiratory, cardiovascular, genitourinary, gastrointestinal, and nervous systems. Epstein-Barr virus also plays a significant role in pathogenesis of autoimmune diseases, allergies, and neoplasms, with Burkitt lymphoma as the main representative of the latter. The mechanisms of these manifestations are still unresolved. Therefore, the main suggestions are direct viral invasion and chronic immune response due to the reactivation of the latent state of the virus, or even various DNA mutations. Physicians should be cautious about uncommon presentations of the viral infection and consider EBV as a causative agent when they encounter similar clinical pictures.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ecuador 1 <1%
Brazil 1 <1%
Unknown 103 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 17%
Student > Master 15 14%
Researcher 12 11%
Student > Doctoral Student 8 8%
Student > Postgraduate 8 8%
Other 15 14%
Unknown 29 28%
Readers by discipline Count As %
Medicine and Dentistry 35 33%
Agricultural and Biological Sciences 10 10%
Biochemistry, Genetics and Molecular Biology 9 9%
Immunology and Microbiology 6 6%
Nursing and Health Professions 3 3%
Other 7 7%
Unknown 35 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2021.
All research outputs
#15,739,529
of 25,374,647 outputs
Outputs from Jornal de Pediatria
#412
of 896 outputs
Outputs of similar age
#214,103
of 403,316 outputs
Outputs of similar age from Jornal de Pediatria
#8
of 15 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 896 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 403,316 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.