Title |
Detection of Neisseria meningitidis in asymptomatic carriers in a university hospital from Brazil
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Published in |
Revista Argentina de Microbiología, November 2015
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DOI | 10.1016/j.ram.2015.08.004 |
Pubmed ID | |
Authors |
Carolina A. Coch Gioia, Ana P. Silva de Lemos, Maria C. Outeiro Gorla, Raul A. Mendoza-Sassi, Teresa Ballester, Andrea Von Groll, Bruna Wedig, Nathalia de Vargas Ethur, Letícia Bragança, Lucimar Gonçalves Milagres, Pedro E. Almeida da Silva |
Abstract |
Asymptomatic meningococcus carriers in hospitals is a risk factor for acquiring meningococcal disease. Meningococcal carrier (MC) frequency was investigated in oropharyngeal swab samples collected from 200 staff members at a teaching hospital from Brazil. MC prevalence was 9% (95% CI 5-13%). Risk factors associated with MC were: mean age of 26.5 years, male gender, bar attendance frequency and number of persons/house. Of 18 isolated meningococcal strains, 14 were non-groupable (NG), 3 corrresponded to serogroup B and 1 to serogroup 29E. The frequency of serotypes and serosubtypes was heterogenous, with a slight predominance of serotypes 4 and 7 and serosubtypes P1.7 and P1.5. Most strains (n=13) were susceptible to the antimicrobials tested. The ctrA gene (PCR) was identified in 9 (64.3%) of the 14 NG strains, suggesting virulence in most of the NG isolated strains. Therefore, a constant surveillance of these asymptomatic carriers is required. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 2 | 9% |
Professor | 1 | 5% |
Unknown | 19 | 86% |
Readers by discipline | Count | As % |
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Environmental Science | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Medicine and Dentistry | 1 | 5% |
Unknown | 19 | 86% |